Foscarnet sodico dosificacion, efectos secundarios infosida. Intravitreal administration to patients with cmv retinitis has been reported. Foscarnet must be given intravenously, and side effects including nausea, fever, headache, anemia, and renal failure are common. Foscarnet is superior to vidarabine in the treatment of acyclovirresistant hsv infections in patients with aids, and remains a treatment of choice for this illness at a dose of 40 mgkg three times daily 96. Individually dispensed doses of foscarnet should be aseptically transferred and diluted with equal parts of 0. Antivirales universidad centroccidental lisandro alvarado. Inyectar foscarnet demasiado rapido puede causar efectos secundarios peligrosos o no deseados. Foscarnet injection comes as a liquid to be intravenously into a vein. It is classified as a pyrophosphate analog dna polymerase inhibitor. Over 10 million scientific documents at your fingertips.
If your institution subscribes to this resource, and you dont have a myaccess profile, please contact your librarys reference desk for information on how to gain access to this resource from offcampus. When peripheral veins are used, the solution of foscarnet 24 mgml must be diluted. If you are to receive foscarnet at home, the diluted foscarnet intravenous solution should be kept at room temperature 15 30 c. The length of your treatment depends on how you respond to the medication. Composicion, indicaciones, presentacion y contraindicaciones. Australian injectable drugs handbook 7th edition update december 2017 229 foscarnet synonyms foscarnet sodium brand name foscavir drug class antiviral availability glass bottle contains 6g250ml of foscarnet sodium hexahydrate.
Foscarnet update december 2017 the society of hospital. A type of abnormal heartbeat prolonged qt interval has happened with foscarnet. Foscarnet is the conjugate base of a chemical compound with the formula ho 2 cpo 3 h 2. Foscarnet richet indicaciones, dosificacion, presentacion. You may receive foscarnet injection in a hospital or you may administer the medication at home. Call your doctor right away if you have a fast or abnormal heartbeat, or if you pass out. It is usually infused slowly over 1 to 2 hours every 8 or 12 hours.
Jan 26, 2020 a type of abnormal heartbeat prolonged qt interval has happened with foscarnet. Foscarnet sodico appare come una polvere cristallina biancastra contenente 6 equivalenti di acqua di idratazione e formula molecolare na3co5p 6 h2o di peso molecolare pari a a 300,1 grammi mole. Foscarnet dosages must be adjusted according to renal function. Foscarnet phosphonomethanoic acid is an antiviral medication which is primarily used to treat viral infections involving the herpesviridae family. You may receive foscarnet injection in a hospital or. It is recommended that the solution be used within 24 hours of dilution. Foscarnet has in vitro activity against human herpesvirus 6a and 6b, and has been used in a few cases. Penciclovir, ganciclovir, trifluridina, idoxiuridina y vidarabina. Clinically, foscarnet is employed almost exclusively to treat infections with cytomegalovirus cmv particularly when ganciclovir cannot be used and acyclovirresistant herpes simplex virus hsv and varicella zoster virus vzv.
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